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科研論文

公司研發(fā)團隊在全球頂級學術期刊《Nature Materials》、《Nature Communications》、《Cell Research》等系列發(fā)表“載藥囊泡治療腫瘤技術”相關文章20余篇，引用次數(shù)高達4000余次，最高單篇影響因子達38以上。

2020.07
題為Chemotherapeutic Tumor Microparticles Elicit a Neutrophil Response Targeting Malignant Pleural Effusions在 Cancer Immunology Research 雜志上發(fā)表。 (IF: 8.728 )

2020.07
題為Mobilization of neutrophils by MTX-packaging tumor microparticles confers treatment efficacy for obstructive cholangiocarcinoma 在Nature Biomedical Engineering雜志上發(fā)表。 (IF: 18.952 )

2019.10
題為Macrophages reprogrammed by lung cancer microparticles promote tumor development via release of IL-1β 在Cellular & Molecular Immunology 雜志上發(fā)表。 (IF: 8.484)

2019.05
題為The softness of tumour-cell-derived microparticles regulates their drug-delivery efficiency 在Nature Biomedical Engineering 雜志上發(fā)表。 (IF: 18.952)

2019.01
題為Autologous tumor cell–derived microparticle-based targeted chemotherapy in lung cancer patients with malignant pleural effusion 在 Science Translational Medicine 雜志上發(fā)表。 (IF: 16.304)

2018.09

題為Circulating tumor microparticles promote lung metastasis by reprogramming inflammatory and mechanical niches via a macrophage-dependent pathway在 Cancer Immunology Research 雜志上發(fā)表。 (IF: 8.728)

2018.09

題為Mechanisms underlying presentation of tumor microparticle antigens to CD8+ T cells by dendritic cells在 Cancer Immunology Research 雜志上發(fā)表。(IF: 8.728)

2017.03

題為Chemotherapeutic tumor microparticles combining low dose irradiation reprogram tumor-promoting macrophages through a tumor-repopulating cell-curtailing pathway在 OncoImmunology 雜志上發(fā)表。(IF: 5.869)

2017.01

題為Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity在 OncoImmunology 雜志上發(fā)表。(IF: 5.869)

2017.01

題為Pre-instillation of tumor microparticles enhances intravesical chemotherapy of nonmuscle-invasive bladder cancer through a lysosomal pathway在 Biomaterials 雜志上發(fā)表。 (IF=10.317)

2016.06

題為Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles在 Cell Research 雜志上發(fā)表。(IF=20.507)

2016 .05

題為Delivery of oncolytic adenovirus into thenucleus of tumorigenic cells by tumor microparticles for virotherapy 在 Biomaterials 雜志上發(fā)表。 (IF=10.317)

2016 .02

題為Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression 在雜志上 Oncoimmunology 發(fā)表。(IF: 5.869)

2015 .05

題為Tumor cell-derived microparticles: a new form of cancer vaccine在 Oncoimmunology 雜志上發(fā)表。(IF: 5.869)

2015 .04

題為Microparticles mediate human papillomavirus type 6 or 11 infection of human macrophages 在 Cellular & Molecular Immunology 雜志上發(fā)表。(IF: 8.484)

2015 .02

題為Cell-free tumor microparticle vaccines stimulate dendritic cells via cGAS/STING signaling 在 Cancer Immunology Research 雜志上發(fā)表。(IF: 8.728)

2012 .12

題為Delivery of chemotherapeutic drugs in tumourcell-derived microparticles 在Nature Communications上發(fā)表。 (IF: 12.121)

2012.10

題為Microparticles released by Listeria monocytogenes-infected macrophages are required for dendritic cell-elicited protective immunity在 Cellular & Molecular Immunology 上發(fā)表。(IF: 8.484)

2012 .08

題為TLR4 signaling induces the release of microparticles by tumor cells that regulate inflammatory cytokine IL-6 of macrophages via microRNA let-7b 在OncoImmunology上發(fā)表。(IF: 5.869)

2012 .07

題為Soft fibrin gels promote selection and growth of tumorigenic cells 在 Nature Materials 上發(fā)表。(IF: 38.663)

2010 .10

題為Innate Immune Cell-Derived Microparticles Facilitate Hepatocarcinoma Metastasis by Transferring Integrin aMb2 to Tumor Cells 在 Journal Immunology 上發(fā)表。 (IF: 4.886)

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